Nattokinase for Heart Health: Benefits, Dosage, and the Best Supplements to Try

Nattokinase is a powerful enzyme extracted from natto, a traditional Japanese fermented soybean dish. It has been studied for its ability to support healthy blood flow and cardiovascular function. If you are looking for a natural way to support your heart, nattokinase may be worth exploring.

Researchers have found that nattokinase may help break down fibrin, a protein involved in blood clotting. This makes it a popular choice among people seeking natural cardiovascular support. Studies suggest it may also help maintain healthy blood pressure levels when taken consistently.

What Is Nattokinase and Where Does It Come From?

Nattokinase was first discovered in 1987 by Dr. Hiroyuki Sumi while he was researching natural blood clot dissolvers. He found that natto, a sticky fermented soybean food eaten in Japan for centuries, contained a potent fibrinolytic enzyme.

The enzyme is produced during the fermentation of soybeans with Bacillus subtilis bacteria. While natto itself is an acquired taste, nattokinase supplements offer the same enzyme in an easy to take capsule form. Most supplements are measured in fibrinolytic units (FU), with common doses ranging from 2,000 to 4,000 FU per serving.

Key Benefits of Nattokinase for Heart Health

Research suggests nattokinase offers several potential benefits for cardiovascular health. Here is what the science shows so far.

May Support Healthy Blood Flow

Nattokinase may help break down fibrin, which is a protein that can build up in blood vessels over time. By supporting the body’s natural fibrin management, it may help maintain smooth and healthy circulation. A 2022 study published in the Journal of Atherosclerosis and Thrombosis found that nattokinase supplementation was associated with improved markers of blood flow.

May Help Maintain Healthy Blood Pressure

Several studies suggest nattokinase may help support blood pressure levels already within a normal range. A meta-analysis published in Biomarker Insights found that participants taking nattokinase showed modest improvements in both systolic and diastolic blood pressure compared to placebo groups.

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Double Wood Supplements is a trusted brand known for quality sourcing and third-party testing. Their nattokinase provides 4,000 FU per serving, which falls within the most commonly studied dosage range. Users frequently report noticing improved circulation within the first few weeks. The capsules are easy to swallow, and the 120-count bottle provides a solid two-month supply at the recommended dose.

Double Wood Nattokinase 4,000 FU Attributes

• 4,000 FU per serving from Japanese natto
• 120 vegetarian capsules per bottle
• Third-party tested for purity and potency
• Manufactured in the USA in a GMP facility

How to Take Nattokinase Safely

Most studies use doses between 2,000 and 4,000 FU per day. It is generally recommended to take nattokinase on an empty stomach, either first thing in the morning or before bed. This allows the enzyme to enter the bloodstream more efficiently.

It is important to talk with your healthcare provider before starting nattokinase, especially if you take blood-thinning medications. Nattokinase may enhance the effects of anticoagulants, so medical guidance is essential for safe use.

Who Should Avoid Nattokinase?

People taking warfarin, aspirin, or other blood thinners should avoid nattokinase unless cleared by a doctor. Pregnant or nursing women should also consult a healthcare provider before use. Those with bleeding disorders or scheduled for surgery should stop taking nattokinase at least two weeks before any procedure.

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Nutricost offers one of the most affordable nattokinase options on the market without sacrificing quality. At 2,000 FU per capsule, it is a great starting point for beginners. The capsules are gluten-free, non-GMO, and vegetarian friendly. Nutricost is a well-known supplement brand, and their nattokinase is manufactured in an FDA-registered facility. With over 2,000 positive reviews, this is a reliable everyday choice.

Nutricost Nattokinase 2,000 FU Attributes

• 2,000 FU per capsule for daily maintenance
• 120 vegetarian capsules per bottle
• Gluten-free, non-GMO, and soy-free formula
• Manufactured in an FDA-registered, GMP-compliant facility

Nattokinase vs Other Heart Supplements

You may be wondering how nattokinase compares to other popular heart health supplements. Fish oil and CoQ10 are commonly used for cardiovascular support, but they work in different ways.

Fish oil primarily supports healthy triglyceride levels and reduces inflammation. CoQ10 supports cellular energy production in the heart muscle. Nattokinase works on a different pathway by targeting fibrin and supporting healthy blood viscosity. Many people choose to combine nattokinase with these other supplements for a comprehensive approach. If you are interested in learning more about natural heart support, check out our article on ginger for inflammation, which also supports cardiovascular health.

Choosing the Right Nattokinase Supplement

When shopping for nattokinase, look for products that clearly state the FU count per serving. Third-party testing is also important for quality assurance. Most research supports a daily dose of 2,000 to 4,000 FU for general cardiovascular support.

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Doctor’s Best uses NSK-SD, a patented form of nattokinase that has been used in clinical research. This sets it apart from generic nattokinase products. The 270-count bottle is a great value for those who plan to take nattokinase long term. It is non-GMO, vegan, and gluten-free. Doctor’s Best is one of the most respected supplement brands, and their commitment to science-backed formulations shows in this product.

Doctor’s Best Nattokinase Attributes

• Uses patented NSK-SD nattokinase
• 270 vegan capsules for extended supply
• Non-GMO, vegan, and gluten-free
• Backed by clinical research and third-party testing

Final Thoughts on Nattokinase for Heart Health

Nattokinase is a promising natural enzyme that may support healthy blood flow and cardiovascular function. It has a long history rooted in Japanese food culture and growing scientific backing. Whether you are just starting to explore heart health supplements or looking to add something new to your routine, nattokinase is worth considering.

As always, talk with your doctor before starting any new supplement, especially if you have an existing health condition or take medications.

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